Prof. Kironde (C.B.E, B.Sc.,M. Ed.) was the first Ugandan to head the Institution as Principal. He was a Lecturer of education at Makerere. He served until 1970 when the different Colleges comprising UEA were made independent national Universities.
In 1970, Makerere University was designated as an Independent National University from the federation previously known as UEA.
In 1985 Prof. Yusuf Lule Kironde succumbed to kidney failure.